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Human Histologic Evaluation of Anorganic Bovine Bone Mineral Combined with Recombinant Human Platelet-Derived Growth Factor BB in Maxillary Sinus Augmentation: Case Series Study Human Histologic Evaluation of Anorganic Bovine Bone Mineral Combined with Recombinant Human Platelet-Derived Growth Factor BB in Maxillary Sinus Augmentation: Case Series Study

Author(s):

David Garber, DMD;Maurice Salama, DMD;Steven S. Wallace, DDS;Myron Nevins, DDS;James J. Hanratty, DDS; Bradley S. McAllister, DDS; Marc L. Nevins, DMD, MMSc; Peter Schupbach, PhD; Simon M. Bernstein, DDS, MS; David M. Kim, DDS, DMSc

Date Added:

12/9/2009


Summary:

The objective of this proof-of-principle study was to examine the potential for improved bone regenerative outcomes in maxillary sinus augmentation procedures when recombinant human platelet-derived growth factor BB (0.3 mg/mL) is combined with particulate anorganic bovine bone mineral. The surgical outcomes in all treated sites were uneventful at 6 to 8 months, with sufficient regenerated bone present to allow successful placement of maxillary posterior implants.

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